The best way to play is through the official Grand Theft Auto: San Andreas available on the Google Play Store or the Apple App Store.
To play these, you can download the ISO files (or extract them from your own discs), move them to your "PSP Games" folder, and open them in the PPSSPP Emulator .
These are fan-made projects built on the engine of official PSP titles like GTA: Liberty City Stories or GTA: Vice City Stories . These mods swap textures, cars, and maps to mimic the look of San Andreas.
Some popular online tutorials showing "San Andreas on PSP" are well-known April Fool's pranks or edited footage using other emulators. Recommended Alternatives for Mobile Gaming
Many "highly compressed" (e.g., 70 MB or 100 MB) zip files found on unverified sites can contain malware or empty data, as the actual game data for San Andreas typically requires over 2 GB of space.