In 2022, Jamilla starred in the Vivamax series Iskandalo , where she played Belinda Chuatico. The show's title itself generates search traffic that users often confuse for real-life events.

She was a regular in hit series such as Mara Clara (2010), where she played Lenita Santos, and Nasaan Ka, Elisa? (2011).

Jamilla, along with co-stars like AJ Raval, has publicly expressed frustration over "spliced" or edited videos from her movies being circulated on social media to look like real-life leaked footage.